Uji Sensitivitas Bakteri pada Pasien Infeksi Saluran Kemih Terkait Kateter terhadap Antibiotik Amoksisilin dan Seftriakson

Abstract

Background: Urinary tract infections (UTIs) are disorders caused by microorganisms that multiply in the urinary tract. UTIs are often associated with catheter use. Catheter-associated UTIs are the most common type of nosocomial infection found in hospitals. Treatment of bacterial infections is generally with antibiotic therapy; however, inappropriate and irrational use of antibiotics results in the emergence of antibiotic resistance.

Purpose: This study was aim to determine the sensitivity patterns of bacteria causing catheterization-associated urinary tract infections to the antibiotic’s amoxicillin and ceftriaxone.

Method: The design of study was an an analytical observational study. his study used urine samples from 60 patients with catheterized UTIs. Identification of the bacterial profile causing previous urinary tract infections was carried out, followed by antibiotic sensitivity testing using the antibiotic disc diffusion method. The diameter of the formed clear zone was measured and categorized according to CLSI standards.

Result: The results of this study showed that the microorganisms causing catheterized urinary tract infections were mostly still sensitive to amoxicillin and ceftriaxone antibiotics, with 27 (22.5%) isolates and 10 (8.33%) bacterial isolates, respectively. The results showed that 22 (18.83%) were resistant to amoxicillin and 5 (4.17%) were resistant to ceftriaxone.

Conclusion: Amoxicillin still shows sensitivity to bacteria that cause urinary tract infections.